Semler Scientific (NASDAQ: SMLR), a medical equipment firm, has expanded its bitcoin holdings with the acquisition of 455 BTC over the 10-day period ending May 22. The purchase, valued at $50 million and executed at an average price of $109,801 per bitcoin, marks the company’s third-largest bitcoin buy since adopting a bitcoin standard nearly a year ago.
The acquisition was financed through Semler’s ongoing at-the-market (ATM) equity offering, initiated in April. Since launching the $500 million ATM program on April 15, the company has issued 3,003,488 shares, raising approximately $114.8 million to date.
This latest purchase brings Semler’s total bitcoin holdings to 4,264 BTC, acquired at a cumulative cost of $390 million. At current market prices, the holdings are now worth over $450 million.
The company’s BTC Yield—a metric increasingly used by bitcoin-holding firms to gauge performance—has climbed to 25.8% in 2025. BTC Yield measures the year-to-date percentage change in the ratio of total bitcoin holdings to assumed diluted shares outstanding, reflecting Semler’s growing leverage to bitcoin’s performance.
Despite the bullish accumulation, Semler shares (SMLR) fell 5.3% in premarket trading Friday, mirroring a broader dip in crypto markets as bitcoin slipped to $108,300 following renewed macroeconomic tensions.
